Myalgic encephalomyelitis (ME, also known as ME/CFS) and long COVID are highly complex chronic conditions.
PrecisionLife has undertaken multiple landmark studies in ME and long COVID and identified the first reproducible disease mechanisms and clinically actionable patient subgroups for both conditions.
These studies include the most detailed genetic analysis of ME ever performed, identifying over 250 core genes associated with the disease, revealing clear areas of biological overlap with long COVID, and discovering multiple drug repurposing opportunities with biomarker tests to find the patients who would most likely benefit from them.
With this new understanding, we're driving better diagnosis, treatment, and prevention of these debilitating diseases.
Learn about this foundational research
Identification of Novel Reproducible Combinatorial Genetic Risk Factors for Myalgic Encephalomyelitis in the DecodeME Patient Cohort and Commonalities with Long COVID
Journal of Translational Medicine
Authors: J Sardell, S Das, M Pearson, D Kolobkov, A Malinowski, L Fullwood, M Sanna, H Baxter, K McLellan, M Natt, D Lamirel, S Chowdhury, M Strivens, S Gardner.
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Our other ME/CFS and long COVID studies |
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ME/CFS & Long COVID: Genetics, Tests, GLP-1s & other Drugs |
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Reproducibility of Genetic Risk Factors Identified for Long COVID using Combinatorial Analysis Across US and UK Patient Cohorts with Diverse Ancestries |
Genetic Risk Factors for ME/CFS, Long COVID & their Similarities |
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Genetic Risk Factors for Severe and Fatigue Dominant Long COVID and Commonalities with ME/CFS Identified by Combinatorial Analysis |
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Solving the ME/CFS and Long COVID Jigsaw Puzzle |
New Study Links 14 Genes to ME/CFS |
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Data partners
